Plasmablastic Lymphoma vs Myeloma With Plasmablastic Morphology: An Ongoing Diagnostic Dilemma
نویسندگان
چکیده
منابع مشابه
Plasmablastic plasma cell myeloma mimicking plasmablastic lymphoma
which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. A 54-year-old woman was admitted with compression fracture of thoracic vertebral bodies. Urine protein electro-phoresis revealed the presence of M protein and serum free κ/λ ratio was 0.01. Bone marrow aspiration (A) and biopsy (B) revealed diffuse infiltrat...
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Plasmablastic myeloma (PBM) is a rare, monoclonal, immunoproliferative plasma cell neoplasm that shares many characteristics with plasmablastic lymphoma (PBL) [1]. Currently, there are no set standards for differentiating between PBL and PBM. Morphologically, PBM is characterized by the presence of large plasma cells with large hyperchromatic nuclei, one or more prominent centrally-located nucl...
متن کاملPlasmablastic Myeloma versus Plasmablastic Lymphoma: Different Yet Related Diseases
Plasmablastic myeloma (PBM) is a rare, monoclonal, immunoproliferative plasma cell neoplasm that shares many characteristics with plasmablastic lymphoma (PBL) [1]. Currently, there are no set standards for differentiating between PBL and PBM. Morphologically, PBM is characterized by the presence of large plasma cells with large hyperchromatic nuclei, one or more prominent centrally-located nucl...
متن کاملPlasmablastic lymphoma
BACKGROUND Plasmablastic lymphoma (PBL) is a B-cell malignancy associated with human immunodeficiency virus (HIV). PBL could also influence the HIV-negative patients. The study aimed to identify prognostic factors for survival among Chinese PBL patients. MATERIALS AND METHODS Eligible patients from literature and Peking Union Medical College Hospital (PUMCH) were included in this study. Clini...
متن کاملPlasmablastic lymphoma with unfavorable chromosomal abnormalities related to plasma cell myeloma: A borderline case between plasmablastic lymphoma and plasmablastic plasma cell myeloma
Plasmablastic lymphoma (PBL) is an aggressive subtype of DLBCL, first reported in HIV-infected patients1 and subsequently recognized in the WHO 2008 classification.2 PBL often arises in the oral cavity, but other sites include the nasal cavity, GI tract, skin, bone, and lungs.3-5 PBL mainly affects those with immunodeficiency,3-5 but can affect some immunocompetent individuals.6 Histologically,...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2015
ISSN: 0002-9173,1943-7722
DOI: 10.1093/ajcp/144.suppl2.125